Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract. Signs and symptoms often include abdominal pain, diarrhea, fever, and weight loss, and possible bowel obstruction. Other complications may occur outside the gastrointestinal tract and include anemia, skin rashes, arthritis, and tiredness. Crohn's disease is caused by a combination of environmental, immune and bacterial factors in genetically susceptible individuals. It results in a chronic inflammatory disorder, in which the body's immune system attacks the gastrointestinal tract possibly directed at microbial antigens.
The worst Ebola outbreak on record has killed 9,000 in West Africa. But all it took was a few Ebola patients in the United States to show how unprepared we were here, particularly because there weren't any approved vaccines or drugs available to fight the disease.
Now, more than a year after the epidemic hit, clinical trials are at last underway in West Africa. One of the drugs to be tested is called ZMapp and it was used last year to treat nine patients. Only nine because that's all the ZMapp there was at the time...hardly enough to make a dent in the epidemic. So the question now is: Will we be prepared for the next one?