Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract. Signs and symptoms often include abdominal pain, diarrhea, fever, and weight loss, and possible bowel obstruction. Other complications may occur outside the gastrointestinal tract and include anemia, skin rashes, arthritis, and tiredness. Crohn's disease is caused by a combination of environmental, immune and bacterial factors in genetically susceptible individuals. It results in a chronic inflammatory disorder, in which the body's immune system attacks the gastrointestinal tract possibly directed at microbial antigens.
Experimental Ebola Treatment Zmapp To Enter Human Testing
Mapp Biopharmaceutical Inc.s Ebola drug will soon enter human trials in the U.S. and Liberia following successful efforts to boost production capacity, U.S. health officials said.
Early-stage human trials of ZMapp, which may have helped patients such as American aid worker Kent Brantly survive Ebola, will begin within the next three weeks, according to Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases. The U.S. Biomedical Advanced Research and Development Authority has helped Kentucky BioProcessing LLC, a unit of Reynolds American Inc., to produce enough of the drug for the trials, said BARDA Director Robin Robinson.